Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 1/20 | 0.63 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760828 | 0.84 | MMP9 (0.54) | MMP2MMP9GSK3AGSK3BPOLB | |
| SCHEMBL1760840 | 0.84 | MMP9 (0.54) | MMP2MMP9GSK3AGSK3BPOLB | |
| SCHEMBL3098454 | 0.81 | MMP2 (0.53) | MMP2MMP9EHMT2GSK3AGSK3B | |
| SCHEMBL5161712 | 0.80 | MEN1 (0.48) | MMP2MMP9EHMT2GSK3AGSK3B | |
| SCHEMBL3088377 | 0.77 | MMP2 (0.49) | MMP2MMP9EHMT2GSK3AGSK3B | |
| SCHEMBL2535135 | 0.77 | EHMT2 (0.47) | EHMT2GRM6CYP2C19CYP2C9ACE | |
| SCHEMBL2535132 | 0.77 | EHMT2 (0.47) | EHMT2GRM6CYP2C19CYP2C9ACE | |
| SCHEMBL6087639 | 0.76 | MMP2 (0.40) | MMP2MMP9POLBACEKMT2A | |
| SCHEMBL3092558 | 0.75 | EHMT2 (0.50) | MMP2MMP9EHMT2GSK3AGSK3B | |
| SCHEMBL289574 | 0.74 | P2RX7 (0.56) | CYP2C19CYP2C9CYP3A4TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799929-B2 | Biotin intermediate and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| EP-1462444-B1 | INTERMEDIATE FOR BIOTIN AND PROCESS FOR PRODUCING THE SAME | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-2098528-A2 | Biotin intermediate and process for preparing the same | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20080119655-A1 | Biotin intermediate and process for preparing the same | SEKI MASAHIKO | 2008-05-22 | — | — | US | disclosed |
| US-7335778-B2 | Intermediate for biotin and process for producing the same | TANABE SEIYAKU CO., LTD. (JP) | 2008-02-26 | — | — | US | disclosed |
| CN-1273453-C | biotin intermediate and preparation method thereof | TANABE SEIYAKU CO (JP) | 2006-09-06 | — | — | CN | disclosed |
| US-20050038260-A1 | Intermediate for biotin and process for producing the same | API CORPORATION (JP) | 2005-02-17 | — | — | US | disclosed |
| CN-1564813-A | biotin intermediate and preparation method thereof | TANABE SEIYAKU CO (JP) | 2005-01-12 | — | — | CN | disclosed |
| EP-1462444-A1 | INTERMEDIATE FOR BIOTIN AND PROCESS FOR PRODUCING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119655-A1 | Biotin intermediate and process for preparing the same | BTD, BOLA2; BOLA2B, BCAT1 | MMP2 3977/4885MMP9 4356/4885EHMT2 308/4885 |
| US-20050038260-A1 | Intermediate for biotin and process for producing the same | BTD, BCAT1, HLCS | MMP2 3330/4885MMP9 4093/4885EHMT2 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.