Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.53 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.53 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.53 |
| ▸ | GPR27 | Q9NS67 | 5/20 | 0.53 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31610152 | 0.84 | TP53 (0.56) | MAPK1MAPTALDH1A1LMNA | |
| SCHEMBL27181624 | 0.82 | MAPT (0.80) | MAPK1MAPTMEN1KMT2ASLC10A2 | |
| SCHEMBL31610032 | 0.81 | TP53 (0.63) | MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL27180015 | 0.81 | GPR27 (0.61) | MAPK1MAPTMEN1KMT2AGPR27 | |
| SCHEMBL30926865 | 0.81 | GPR27 (0.61) | MAPK1MAPTMEN1KMT2AGPR27 | |
| SCHEMBL31609945 | 0.78 | ALDH1A1 (0.71) | MAPK1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL31610121 | 0.77 | NAMPT (0.65) | MAPTMEN1KMT2AGPR27AVPR2 | |
| SCHEMBL15879829 | 0.76 | SLC10A2 (0.61) | MAPK1MAPTMEN1KMT2ASLC10A2 | |
| SCHEMBL22863019 | 0.75 | MEN1 (0.73) | MAPK1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28393224 | 0.75 | PHGDH (0.64) | MAPK1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179013-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. | 2025-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179013-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | DHX9, DHX29, DDX39B | MAPK1 3598/4885MAPT 3830/4885MEN1 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.