Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RGS4 | P49798 | 1/20 | 0.49 |
| ▸ | RGS8 | P57771 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928899 | 0.96 | ADORA2A (0.55) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL30928887 | 0.86 | ALDH1A1 (0.55) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL30928890 | 0.84 | ALDH1A1 (0.65) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL30928921 | 0.83 | ALDH1A1 (0.62) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL30928909 | 0.83 | TDP2 (0.55) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL30928912 | 0.83 | ALDH1A1 (0.57) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL30928934 | 0.82 | FAAH (0.50) | MEN1KMT2ANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30928916 | 0.82 | ALDH1A1 (0.53) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL30928900 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL30928898 | 0.79 | ALDH1A1 (0.67) | MEN1KMT2AHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184594-A | Preparation method of aza-uracil compound, and compound prepared by same and application of aza-uracil compound | 杭州医学院 | 2024-06-14 | — | — | CN | disclosed |