SCHEMBL30929181

SCHEMBL30929181

O=[N+]([O-])c1ccc(S(=O)(=O)NC23CC(C2)C3)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
CA2 P00918 7/20 0.53
CA1 P00915 5/20 0.53
CA12 O43570 4/20 0.53
CA9 Q16790 4/20 0.53
CA14 Q9ULX7 3/20 0.53
CA3 P07451 2/20 0.53
CA4 P22748 2/20 0.53
CA6 P23280 2/20 0.53
CA5A P35218 2/20 0.53
CA7 P43166 2/20 0.53
CA13 Q8N1Q1 2/20 0.53
CA5B Q9Y2D0 2/20 0.53
MMP2 P08253 2/20 0.53
MMP1 P03956 1/20 0.53
MMP9 P14780 1/20 0.53
MMP8 P22894 1/20 0.53
MMP13 P45452 1/20 0.53
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31143759 0.94 ALDH1A1 (0.66) ALDH1A1LMNACA2CA1CA12
SCHEMBL19798651 0.82 LMNA (0.49) ALDH1A1LMNACA2CA1CA12
SCHEMBL4069630 0.79 CA2 (0.56) ALDH1A1LMNACA2CA1CA12
SCHEMBL15892102 0.75 ALDH1A1 (0.47) ALDH1A1LMNACA2CA1MMP2
SCHEMBL31143800 0.74 HDAC3 (0.58) ALDH1A1LMNACA2CA1CA12
SCHEMBL27221171 0.73 CA2 (0.56) ALDH1A1CA2CA1CA12CA9
SCHEMBL10494215 0.73 CA2 (0.70) LMNACA2CA1CA12CA9
SCHEMBL31143638 0.72 LMNA (0.71) ALDH1A1LMNACA2CA1CA12
SCHEMBL31143809 0.72 LMNA (0.71) ALDH1A1LMNACA2CA1MMP2
SCHEMBL19807188 0.72 LMNA (1.00) ALDH1A1LMNACA2CA1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154169-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. 2025-05-15 US disclosed
EP-4395892-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING Remix Therapeutics Inc. (US) 2024-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154169-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING RBM17, SNRPA, SNRPA1 ALDH1A1 3559/4885LMNA 324/4885CA2 4843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.