Solriamfetol

Solriamfetol

SCHEMBL30929349

NC(=O)OCC(N)Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 2/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ CYP2D6 P10635 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ EPHX1 P07099 2/20 0.55
▸ MMP2 P08253 4/20 0.53
▸ ALPI P09923 1/20 0.52
▸ PTGS1 P23219 1/20 0.52
▸ XIAP P98170 1/20 0.52
▸ SLC7A5 Q01650 1/20 0.52
▸ LMNA P02545 1/20 0.50
▸ SCN4A P35499 2/20 0.49
▸ ANPEP P15144 1/20 0.48
▸ SRR Q9GZT4 2/20 0.47
▸ SLC1A3 P43003 1/20 0.47
▸ SLC1A2 P43004 1/20 0.47
▸ SLC1A1 P43005 1/20 0.47
▸ TACR1 P25103 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Solriamfetol SCHEMBL42525 1.00 PKM (0.56) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL42526 1.00 PKM (0.56) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL30929348 1.00 PKM (0.56) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL2739637 1.00 PKM (0.56) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL4987496 0.98 PKM (0.54) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL28413501 0.98 PKM (0.54) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL8426383 0.98 PKM (0.54) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL8430382 0.98 PKM (0.54) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL30518836 0.97 PKM (0.53) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1
Solriamfetol SCHEMBL30518840 0.95 PKM (0.51) PKMCYP1A2CYP2D6SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688731-A1 PROCESS FOR PREPARING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE INKE, S.A. (ES) 2026-02-11 — — EP disclosed
EP-4626417-A1 METHODS AND COMPOSITIONS FOR IMPROVING DRIVING PERFORMANCE AXSOME THERAPEUTICS (US) 2025-10-08 — — EP disclosed
WO-2024208791-A1 PROCESS FOR PREPARING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE INKE, S.A. (ES) 2024-10-10 — — WO disclosed
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