Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 3/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929426 | 0.83 | F2 (0.52) | F2F7F3PREPKMT2A | |
| SCHEMBL30929477 | 0.82 | F2 (0.49) | F2F7F3PREPKMT2A | |
| SCHEMBL30929436 | 0.81 | F2 (0.57) | F2F7F3PREPKMT2A | |
| SCHEMBL31486375 | 0.80 | METAP2 (0.44) | F2KLKB1METAP2P2RX7 | |
| SCHEMBL30929412 | 0.80 | F2 (0.54) | F2F7F3PREPKMT2A | |
| SCHEMBL30929405 | 0.79 | F2 (0.46) | F2F7F3PREPKMT2A | |
| SCHEMBL30929399 | 0.78 | F2 (0.47) | F2F7F3PREPKMT2A | |
| SCHEMBL30929470 | 0.77 | F2 (0.51) | F2F7F3P2RX7CYP3A4 | |
| SCHEMBL30929395 | 0.77 | F2 (0.47) | F2F7F3PREPKMT2A | |
| SCHEMBL30929415 | 0.76 | F2 (0.44) | F2F7F3PREPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626891-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | Omeros Corporation (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118840-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | OMEROS CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |