Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848607 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL31615904 | 0.79 | TTR (0.44) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL31615799 | 0.77 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL17848342 | 0.75 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL17848728 | 0.73 | NR1H2 (0.44) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL4434853 | 0.72 | MAPT (0.60) | ALDH1A1LMNAMAPTKMT2AGAA | |
| SCHEMBL22370558 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL22439450 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL25802786 | 0.72 | MGLL (0.42) | ALDH1A1LMNAMAPT | |
| SCHEMBL17848761 | 0.71 | DRD2 (0.48) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626865-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | Protego Biopharma, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118810-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | PROTEGO BIOPHARMA, INC. (US) | 2024-06-06 | — | — | WO | disclosed |