Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | SETD1B | Q9UPS6 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498822 | 0.82 | PPARG (0.33) | KDM4E | |
| SCHEMBL6506344 | 0.81 | CISD1 (0.33) | NPC1MEN1PKMKMT2AALDH1A1 | |
| SCHEMBL6503874 | 0.78 | KMT2A (0.36) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL6508566 | 0.77 | ALDH1A1 (0.38) | LMNATP53POLBTDP1SMN1; SMN2 | |
| SCHEMBL6505095 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL6499622 | 0.75 | HPGD (0.35) | GAALMNANPC1TDP1SMN1; SMN2 | |
| SCHEMBL6506231 | 0.75 | KMT2A (0.37) | GAAKDM4EPOLBPKMKMT2A | |
| SCHEMBL6429217 | 0.74 | EPHX2 (0.35) | GAATDP1ALDH1A1 | |
| SCHEMBL1605406 | 0.74 | EPHX2 (0.32) | GAATDP1ALDH1A1 | |
| SCHEMBL6501528 | 0.74 | L3MBTL1 (0.36) | LMNANPC1TP53KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| WO-2005075471-A2 | THIAZOL-COMPOUNDS AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | BIOVITRUM AB (SE) | 2005-08-18 | — | — | WO | claimed |
| US-8086644-B2 | Simplifying complex data stream problems involving feature extraction from noisy data | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-12-27 | — | — | US | disclosed |
| US-7805445-B2 | Simplifying complex data stream problems involving feature extraction from noisy data | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-09-28 | — | — | US | disclosed |
| US-20100011192-A1 | SIMPLIFYING COMPLEX DATA STREAM PROBLEMS INVOLVING FEATURE EXTRACTION FROM NOISY DATA | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100011015-A1 | SIMPLIFYING COMPLEX DATA STREAM PROBLEMS INVOLVING FEATURE EXTRACTION FROM NOISY DATA | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-01-14 | — | — | US | disclosed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
| WO-2005075471-A2 | THIAZOL-COMPOUNDS AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | BIOVITRUM AB (SE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | GAA 522/4885LMNA 1964/4885GPR84 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.