Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31142639 | 0.84 | EPHX2 (0.44) | CTSKEPHX2PDE10ABTKKMT2A | |
| SCHEMBL31142648 | 0.84 | EPHX2 (0.44) | CTSKEPHX2PDE10ABTKKMT2A | |
| SCHEMBL29840412 | 0.83 | NPC1 (0.44) | CTSKEPHX2PDE10ABTKKMT2A | |
| SCHEMBL20806445 | 0.82 | KMT2A (0.52) | CTSKEPHX2PDE10ABTKKMT2A | |
| SCHEMBL29952159 | 0.81 | PIM1 (0.44) | CTSKEPHX2PDE10ABTKKMT2A | |
| SCHEMBL27624491 | 0.79 | MAPT (0.57) | DRD2 | |
| SCHEMBL17315459 | 0.79 | CA2 (0.51) | CTSK | |
| SCHEMBL8665014 | 0.78 | CTSK (0.57) | CTSKBTKACACBJAK3DRD2 | |
| SCHEMBL13150055 | 0.78 | GPR119 (0.44) | CTSKEPHX2PDE10AKMT2AL3MBTL1 | |
| SCHEMBL30932042 | 0.77 | USP30 (0.48) | CTSKEPHX2PDE10ABTKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024083111-A1 | NOVEL HETEROCYCLIC COMPOUNDS | 首药控股(北京)股份有限公司 | 2024-04-25 | — | — | WO | disclosed |