SCHEMBL30933446

SCHEMBL30933446

CCCCOCc1cc(F)c(C#Cc2cc(F)c(-c3cc(F)c(C#N)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARA P10276 1/20 0.34
RARB P10826 1/20 0.34
MAPT P10636 1/20 0.33
FFAR1 O14842 2/20 0.33
FFAR4 Q5NUL3 2/20 0.33
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30933435 0.94 TRPV4 (0.30)
SCHEMBL30933440 0.88 KDM4E (0.35) KDM4EHPGD
SCHEMBL30933438 0.85 MAPT (0.42) RARARARBMAPTKDM4EGAA
SCHEMBL29225911 0.81 FFAR1 (0.30) FFAR1FFAR4KDM4EGAAHPGD
SCHEMBL30933449 0.80 MAPT (0.36) RARARARBMAPTFFAR1KDM4E
SCHEMBL30933448 0.80 MAPT (0.36) RARARARBMAPTFFAR1KDM4E
SCHEMBL30933443 0.79 KDM4E (0.35) RARARARBMAPTFFAR1FFAR4
SCHEMBL142121 0.79 RARB (0.44) RARARARBMAPTKDM4EGAA
SCHEMBL29225983 0.78 FFAR1 (0.34) FFAR1FFAR4KDM4EGAAHPGD
SCHEMBL14964550 0.76 RARB (0.45) RARARARBMAPTKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118109209-A High-birefringence ferroelectric liquid crystal molecule with rigid conjugated mesogen and blended high-birefringence ferroelectric liquid crystal material 华南理工大学 2024-05-31 CN disclosed