SCHEMBL30933448

SCHEMBL30933448

CCCOc1cc(F)c(-c2cc(F)c(C#Cc3cc(F)c(C#N)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MGAT2 Q10469 5/20 0.33
MAOB P27338 1/20 0.32
TRPV4 Q9HBA0 1/20 0.32
FFAR1 O14842 1/20 0.31
LTA4H P09960 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
ACACB O00763 1/20 0.30
KAT6A Q92794 1/20 0.30
RARA P10276 1/20 0.30
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30933449 1.00 MAPT (0.36) MAPTALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL30933438 0.95 MAPT (0.42) MAPTALDH1A1HSD17B10KDM4EMEN1
SCHEMBL29225925 0.92 TRPV4 (0.37) MAPTALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL30933437 0.91 ALDH1A1 (0.40) MAPTALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL142121 0.84 RARB (0.44) MAPTALDH1A1MAPK1KDM4EMEN1
SCHEMBL30933441 0.83 FDPS (0.35) MGAT2
SCHEMBL30933435 0.82 TRPV4 (0.30) TRPV4
SCHEMBL25707182 0.82 TRPV4 (0.45) MAPTALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL30933445 0.81 FFAR4 (0.32) ACACB
SCHEMBL140747 0.81 APP (0.36) KDM4EMGAT2TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118109209-A High-birefringence ferroelectric liquid crystal molecule with rigid conjugated mesogen and blended high-birefringence ferroelectric liquid crystal material 华南理工大学 2024-05-31 CN disclosed