SCHEMBL30933440

SCHEMBL30933440

CCOCc1cc(F)c(C#Cc2cc(F)c(-c3cc(F)c(C#N)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TRPV4 Q9HBA0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30933435 0.91 TRPV4 (0.30) TRPV4
SCHEMBL30933446 0.88 RARA (0.34) KDM4EHPGD
SCHEMBL30933448 0.79 MAPT (0.36) KDM4EALDH1A1HPGDHSD17B10TRPV4
SCHEMBL30933449 0.79 MAPT (0.36) KDM4EALDH1A1HPGDHSD17B10TRPV4
SCHEMBL30933436 0.78 KIF11 (0.36) KDM4EALDH1A1HPGD
SCHEMBL30933438 0.77 MAPT (0.42) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL30933445 0.76 FFAR4 (0.32)
SCHEMBL29225982 0.75 KDM4E (0.30) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL29225913 0.73 TACR1 (0.32)
SCHEMBL21596790 0.72 ALDH1A1 (0.38) KDM4EALDH1A1HPGDHSD17B10TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118109209-A High-birefringence ferroelectric liquid crystal molecule with rigid conjugated mesogen and blended high-birefringence ferroelectric liquid crystal material 华南理工大学 2024-05-31 CN disclosed