Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30933757 | 0.99 | PRMT5 (0.46) | PRMT5WDR77SLC2A1EP300MEN1 | |
| Hydrochloric Acid SCHEMBL30933733 | 0.91 | PRMT5 (0.49) | PRMT5WDR77SLC2A1EP300MEN1 | |
| SCHEMBL30933698 | 0.74 | KDM4E (0.46) | TP53 | |
| SCHEMBL25845153 | 0.69 | ALOX5 (0.36) | MEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL10080359 | 0.68 | PRMT5 (0.58) | PRMT5WDR77SLC2A1EP300CXCR4 | |
| SCHEMBL30933773 | 0.68 | CYP2D6 (0.56) | PRMT5WDR77SLC2A1MEN1TP53 | |
| SCHEMBL25844870 | 0.67 | MAOB (0.34) | CYP3A4 | |
| SCHEMBL31507093 | 0.67 | PRMT5 (0.70) | PRMT5WDR77SLC2A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30933803 | 0.67 | CYP1A2 (0.58) | PRMT5WDR77SLC2A1MEN1TP53 | |
| Hydrochloric Acid SCHEMBL30933686 | 0.67 | PRMT5 (0.47) | PRMT5WDR77SLC2A1MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |