Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933720 | 0.92 | DPP4 (0.47) | KDM4EPKMSTSHTR6TGFBR1 | |
| SCHEMBL30933793 | 0.88 | KDM4E (0.48) | KDM4EPKMSTSHTR6TGFBR1 | |
| SCHEMBL30933838 | 0.88 | KDM4E (0.48) | KDM4EPKMSTSHTR6TGFBR1 | |
| SCHEMBL30933768 | 0.84 | KDM4E (0.48) | KDM4EPKMSTSHTR6TGFBR1 | |
| SCHEMBL30933731 | 0.84 | GPR119 (0.53) | KDM4EPKMHTR6TGFBR1SCN9A | |
| SCHEMBL30933815 | 0.83 | STS (0.52) | KDM4EPKMSTSTGFBR1GPR119 | |
| SCHEMBL30933725 | 0.82 | MAPK8 (0.46) | KDM4EPKMSTSHTR6GPR119 | |
| SCHEMBL30933724 | 0.82 | TGFBR1 (0.51) | KDM4EPKMSTSHTR6TGFBR1 | |
| SCHEMBL30933760 | 0.82 | MAPK8 (0.46) | KDM4EPKMSTSHTR6GPR119 | |
| SCHEMBL30933779 | 0.82 | MAPK8 (0.46) | KDM4EPKMSTSHTR6GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |