Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 3/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933725 | 1.00 | MAPK8 (0.46) | MAPK8CYP1A2CYP2D6ANO1BCHE | |
| SCHEMBL30933760 | 1.00 | MAPK8 (0.46) | MAPK8CYP1A2CYP2D6ANO1BCHE | |
| SCHEMBL30933838 | 0.94 | KDM4E (0.48) | MAPK8CYP1A2CYP2D6HTR6KMT2A | |
| SCHEMBL30933746 | 0.93 | HTR6 (0.45) | MAPK8ANO1BCHEHTR6KMT2A | |
| SCHEMBL30933826 | 0.92 | MAPK8 (0.46) | MAPK8ANO1BCHEHTR6KDM4E | |
| SCHEMBL30933771 | 0.87 | PKM (0.47) | MAPK8HTR6KDM4EPKMALDH1A1 | |
| SCHEMBL30933793 | 0.87 | KDM4E (0.48) | MAPK8HTR6KMT2AKDM4EPKM | |
| SCHEMBL30933805 | 0.86 | AHCY (0.48) | MAPK8CYP1A2CYP2D6ANO1AHCY | |
| SCHEMBL4329719 | 0.85 | ALDH1A1 (0.56) | MAPK8KMT2AKDM4EPKMIDO1 | |
| SCHEMBL30933770 | 0.85 | KDM4E (0.47) | MAPK8HTR6KDM4EPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |