Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 11/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 11/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | ITK | Q08881 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632449 | 0.83 | CA1 (0.37) | BTKCA1CA2CA9PDGFRB | |
| SCHEMBL30227001 | 0.81 | TGM2 (0.47) | TGM2BTKITKCXCR2 | |
| SCHEMBL30935033 | 0.81 | TGM2 (0.47) | TGM2BTKITK | |
| SCHEMBL30226989 | 0.81 | CA1 (0.47) | TGM2CA1CA2CA9PDGFRB | |
| SCHEMBL16123326 | 0.81 | PDGFRB (0.42) | FGFR1FGFR4TGM2BTKITK | |
| SCHEMBL15289558 | 0.79 | PDGFRB (0.33) | CA1CA2CA9PDGFRBKDR | |
| SCHEMBL30935246 | 0.78 | LIPE (0.38) | FGFR1FGFR4TGM2BTKCXCR2 | |
| SCHEMBL16100601 | 0.77 | LIPE (0.45) | TGM2BTK | |
| SCHEMBL16667637 | 0.74 | NPC1 (0.40) | CA1CA2CA9PDGFRBKDR | |
| SCHEMBL15271999 | 0.74 | CA1 (0.36) | BTKCA1CA2CA9PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |