SCHEMBL30935699

SCHEMBL30935699

Cc1ccc2c(=O)cc(-c3ccccc3)[nH]c2c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 10/20 0.77
LMNA P02545 7/20 0.77
KDM4E B2RXH2 7/20 0.77
RAB9A P51151 3/20 0.77
SMN1; SMN2 Q16637 3/20 0.77
MAPT P10636 3/20 0.77
TP53 P04637 2/20 0.77
HSD17B10 Q99714 2/20 0.77
NPC1 O15118 2/20 0.77
CTSV O60911 2/20 0.69
CTSL P07711 2/20 0.69
ALDH1A1 P00352 8/20 0.68
TUBB4A P04350 1/20 0.68
TUBB P07437 1/20 0.68
TUBA3C P0DPH7 1/20 0.68
TUBA1B P68363 1/20 0.68
TUBA4A P68366 1/20 0.68
TUBB4B P68371 1/20 0.68
TUBB3 Q13509 1/20 0.68
TUBB2A Q13885 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2799465 0.87 HPGD (1.00) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL2630603 0.83 HPGD (0.76) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL30935678 0.82 HPGD (1.00) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL6534180 0.82 HPGD (1.00) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL29411863 0.81 HPGD (1.00) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL367268 0.81 HPGD (1.00) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL9389628 0.81 LMNA (1.00) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL9390802 0.81 LMNA (1.00) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL6534320 0.80 HPGD (0.79) HPGDLMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL9874774 0.78 MEN1 (1.00) HPGDLMNAKDM4ERAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108771-A Method for preparing quinolone compound by high-efficiency catalysis of pyridine palladium 安康学院 2024-05-31 CN disclosed