Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.78 |
| ▸ | HPGD | P15428 | 9/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | CTSV | O60911 | 2/20 | 0.66 |
| ▸ | CTSL | P07711 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311823 | 0.85 | KDM4E (0.74) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL9389628 | 0.84 | LMNA (1.00) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL9874028 | 0.82 | KMT2A (0.78) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL24686712 | 0.80 | ALDH1A1 (1.00) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL30935678 | 0.80 | HPGD (1.00) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6534180 | 0.80 | HPGD (1.00) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL313903 | 0.79 | ALDH1A1 (0.68) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL30935699 | 0.78 | HPGD (0.77) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6001399 | 0.76 | CTSV (1.00) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL29411879 | 0.76 | CTSV (1.00) | MEN1KMT2AKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |