SCHEMBL2630603

SCHEMBL2630603

O=c1cc(-c2ccccc2)[nH]c2cc3c(=O)cc(-c4ccccc4)[nH]c3cc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 8/20 0.76
LMNA P02545 6/20 0.76
KDM4E B2RXH2 5/20 0.76
CTSV O60911 3/20 0.76
CTSL P07711 3/20 0.76
TP53 P04637 2/20 0.76
HSD17B10 Q99714 2/20 0.76
TUBB4A P04350 1/20 0.76
TUBB P07437 1/20 0.76
TUBA3C P0DPH7 1/20 0.76
TUBA1B P68363 1/20 0.76
TUBA4A P68366 1/20 0.76
TUBB4B P68371 1/20 0.76
TUBB3 Q13509 1/20 0.76
TUBB2A Q13885 1/20 0.76
TUBB8 Q3ZCM7 1/20 0.76
TUBA3E Q6PEY2 1/20 0.76
NPSR1 Q6W5P4 1/20 0.76
TUBA1A Q71U36 1/20 0.76
TUBA1C Q9BQE3 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27923242 0.88 HPGD (0.65) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL367268 0.86 HPGD (1.00) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL29411863 0.86 HPGD (1.00) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL30462937 0.84 HPGD (0.76) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL9390802 0.83 LMNA (1.00) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL30935699 0.83 HPGD (0.77) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL9389628 0.83 LMNA (1.00) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL1273139 0.83 HPGD (0.68) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL30935740 0.83 KMT2A (1.00) HPGDLMNAKDM4ECTSVCTSL
SCHEMBL9385766 0.83 HPGD (0.68) HPGDLMNAKDM4ECTSVCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177901-B2 Porous inorganic materials of silcon and oxygen BASF SE Ludwigshafen (DE) 2012-05-15 US disclosed
US-8177901-B2 Porous inorganic materials of silcon and oxygen BASF SE Ludwigshafen (DE) 2012-05-15 US disclosed
US-20120100395-A1 INDICATOR SYSTEM FOR MONITORING A STERILIZATION PROCESS BASF SE (DE) 2012-04-26 US disclosed
WO-2010128063-A2 INDICATOR SYSTEM FOR MONITORING A STERILIZATION PROCESS BASF SE (DE) 2010-11-11 WO disclosed
US-20100003520-A1 POROUS INORGANIC MATERIALS OF SILCON AND OXYGEN BUJARD PATRICE 2010-01-07 US disclosed
US-20100003520-A1 POROUS INORGANIC MATERIALS OF SILCON AND OXYGEN BUJARD PATRICE 2010-01-07 US disclosed
US-7594962-B2 vapor-deposition of a separating agent (NaCl) onto Al carrier to produce a separating agent layer,simultaneous vapor-deposition of SiO and NaCl onto the NaCl layer, separating SiO, converted to SiO2 by oxidizing with O2, filling pores of SiO2 with TiO2, Fe2O3, Indium tin oxide etc. CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US disclosed
US-7594962-B2 vapor-deposition of a separating agent (NaCl) onto Al carrier to produce a separating agent layer,simultaneous vapor-deposition of SiO and NaCl onto the NaCl layer, separating SiO, converted to SiO2 by oxidizing with O2, filling pores of SiO2 with TiO2, Fe2O3, Indium tin oxide etc. CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US disclosed
US-20080319089-A1 Method of colouring carrier materials MULLER MARTIN 2008-12-25 US disclosed
US-20080319089-A1 Method of colouring carrier materials MULLER MARTIN 2008-12-25 US disclosed
EP-1549714-B1 METHOD OF COLOURING CARRIER MATERIALS CIBA HOLDING INC (CH) 2008-10-29 EP disclosed
US-20070051275-A1 Method of colouring carrier materials CIBA SPECIALTY CHEMICALS CORP. 2007-03-08 US disclosed
US-20070051275-A1 Method of colouring carrier materials CIBA SPECIALTY CHEMICALS CORP. 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319089-A1 Method of colouring carrier materials CRYAA, SLC67A1, SOD3 HPGD 1123/4885LMNA 823/4885KDM4E 4338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.