Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 7/20 | 0.33 |
| ▸ | MAOB | P27338 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790163 | 0.75 | MAOA (0.38) | MEN1KMT2AMAOAMAOBCYP3A4 | |
| SCHEMBL394270 | 0.73 | MAOA (0.41) | MAOAMAOBCYP3A4KDM1ATSHR | |
| SCHEMBL31294910 | 0.72 | MAOA (0.37) | MEN1KMT2AMAOAMAOBCYP3A4 | |
| SCHEMBL20699480 | 0.72 | SLC6A2 (0.34) | MEN1KMT2AMAOAMAOBCYP3A4 | |
| SCHEMBL30668471 | 0.67 | KDM1A (0.30) | KDM1A | |
| SCHEMBL3476384 | 0.67 | HSD11B1 (0.33) | MAOAMAOBCYP3A4MAPTKDM1A | |
| SCHEMBL30311609 | 0.65 | MAOA (0.36) | MAOAMAOBKDM1A | |
| SCHEMBL30668455 | 0.64 | OPRM1 (0.31) | KDM1AOPRM1OPRL1 | |
| SCHEMBL605319 | 0.64 | MAOA (0.34) | MEN1KMT2AMAOAMAOBCYP3A4 | |
| SCHEMBL4304141 | 0.64 | ALDH1A1 (0.35) | MEN1KMT2AMAOAMAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608389-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | Nine Square Therapeutics Corporation (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024092235-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | NINE SQUARE THERAPEUTICS CORPORATION (US) | 2024-05-02 | — | — | WO | disclosed |