Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3334777 | 0.72 | RPS6KA5 (0.44) | RPS6KA5KDM4EHPGDALDH1A1MAPK1 | |
| SCHEMBL2134783 | 0.69 | ALDH1A1 (0.39) | RPS6KA5KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28174563 | 0.68 | MAPT (0.47) | KMT2AMEN1KDM4EHPGDALDH1A1 | |
| SCHEMBL16513320 | 0.67 | RPS6KA5 (0.43) | RPS6KA5KMT2AMEN1KDM4EHPGD | |
| SCHEMBL20162223 | 0.67 | RPS6KA5 (0.35) | RPS6KA5KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL18985809 | 0.65 | AAK1 (0.38) | KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL18985804 | 0.65 | LRRK2 (0.47) | KMT2AMEN1KDM4EHPGDALDH1A1 | |
| SCHEMBL1222435 | 0.65 | SMN1; SMN2 (0.33) | KMT2AKDM4EHPGDALDH1A1POLB | |
| SCHEMBL5021094 | 0.64 | NUDT1 (0.39) | KMT2AMEN1KDM4EHPGDALDH1A1 | |
| SCHEMBL18985485 | 0.63 | JMJD6 (0.39) | KMT2AMEN1KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |