Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
| ▸ | PDXK | O00764 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596581 | 0.79 | SRC (0.35) | TDP1UHRF1 | |
| SCHEMBL35528 | 0.78 | PDXK (0.39) | TDP1TP53PARP1HDAC8GRM5 | |
| SCHEMBL29419055 | 0.78 | PDXK (0.39) | TDP1TP53PARP1HDAC8GRM5 | |
| SCHEMBL34470216 | 0.75 | PARP1 (0.32) | PARP1 | |
| SCHEMBL16623137 | 0.75 | TP53 (0.33) | TDP1TP53PARP1HDAC8GRM5 | |
| SCHEMBL20083747 | 0.75 | PIK3CA (0.34) | TDP1TP53PARP1HDAC8 | |
| SCHEMBL29769000 | 0.72 | TRPA1 (0.34) | TDP1TP53PARP1 | |
| SCHEMBL4226664 | 0.71 | P4HTM (0.50) | TDP1HDAC8 | |
| SCHEMBL4226657 | 0.71 | P4HTM (0.50) | TDP1HDAC8 | |
| SCHEMBL390289 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |