Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GLI1 | P08151 | 1/20 | 0.42 |
| ▸ | GLI2 | P10070 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16123492 | 1.00 | DYRK1A (0.49) | DYRK1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL16123486 | 0.84 | KDM4E (0.47) | DYRK1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL10708983 | 0.82 | MAPT (0.59) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL16102894 | 0.82 | DYRK1A (0.74) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16123491 | 0.82 | DYRK1A (0.55) | DYRK1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL30939881 | 0.82 | DYRK1A (0.74) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL647613 | 0.82 | DYRK1A (0.55) | DYRK1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL8852559 | 0.80 | DYRK1A (0.53) | DYRK1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL646288 | 0.78 | DYRK1A (0.51) | DYRK1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL177685 | 0.77 | CCNB2 (0.68) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-B | Alkylamine harmine derivatives for promoting bone growth | 奥斯菲治疗有限公司 | 2024-07-19 | — | — | CN | disclosed |