Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939970 | 0.84 | DYRK1A (0.49) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL16123492 | 0.84 | DYRK1A (0.49) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL16123491 | 0.79 | DYRK1A (0.55) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL16123495 | 0.79 | DYRK1A (0.74) | KDM4EALDH1A1HPGDDYRK1ACDK5 | |
| SCHEMBL647613 | 0.79 | DYRK1A (0.55) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL30939906 | 0.79 | DYRK1A (0.74) | KDM4EALDH1A1HPGDDYRK1ACDK5 | |
| SCHEMBL8852559 | 0.77 | DYRK1A (0.53) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL646288 | 0.75 | DYRK1A (0.51) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL177685 | 0.75 | CCNB2 (0.68) | KDM4EALDH1A1HPGDDYRK1ACDK5 | |
| SCHEMBL30939928 | 0.75 | CCNB2 (0.68) | KDM4EALDH1A1HPGDDYRK1ACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3915987-B1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOQC INC (CA) | 2023-12-13 | — | — | EP | disclosed |
| EP-3915987-A1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2021-12-01 | — | — | EP | disclosed |
| EP-2968284-B1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOQC INC (CA) | 2021-04-21 | — | — | EP | disclosed |
| US-20200172538-A1 | COMPOUNDS FOR BONE GROWTH | OSSIFI THERAPEUTICS LLC | 2020-06-04 | — | — | US | disclosed |
| US-20170298059-A1 | COMPOUNDS FOR BONE GROWTH | OSSIFI THERAPEUTICS LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170298059-A1 | COMPOUNDS FOR BONE GROWTH | OSSIFI THERAPEUTICS LLC | 2017-10-19 | — | — | US | disclosed |
| US-9540365-B2 | Compounds for bone growth | OSTEOQC INC. (CA) | 2017-01-10 | — | — | US | disclosed |
| US-9540365-B2 | Compounds for bone growth | OSTEOQC INC. (CA) | 2017-01-10 | — | — | US | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140288068-A1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288068-A1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172538-A1 | COMPOUNDS FOR BONE GROWTH | FGF1, FGF2, BMP2 | KDM4E 2795/4885ALDH1A1 655/4885HPGD 47/4885 |
| US-20170298059-A1 | COMPOUNDS FOR BONE GROWTH | FGF1, FGF2, BMP2 | KDM4E 2795/4885ALDH1A1 655/4885HPGD 47/4885 |
| US-20140288068-A1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | TPH1, TPH2, HTR5A | KDM4E 701/4885ALDH1A1 702/4885HPGD 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.