Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30146700 | 0.89 | PNMT (0.42) | PNMTNPC1RAB9AACETGM2 | |
| SCHEMBL7520245 | 0.89 | CTSK (0.41) | PNMTNPC1RAB9ATGM2ITGB3 | |
| SCHEMBL30747802 | 0.89 | CTSK (0.41) | PNMTNPC1RAB9ATGM2ITGB3 | |
| SCHEMBL6560816 | 0.89 | CTSK (0.41) | PNMTNPC1RAB9ATGM2ITGB3 | |
| SCHEMBL30940317 | 0.88 | SIRT2 (0.43) | PNMTNPC1RAB9AACETGM2 | |
| SCHEMBL2549268 | 0.88 | PNMT (0.43) | PNMTNPC1RAB9AACETGM2 | |
| SCHEMBL2549264 | 0.88 | PNMT (0.43) | PNMTNPC1RAB9AACETGM2 | |
| SCHEMBL30562072 | 0.87 | CTSK (0.42) | PNMTNPC1RAB9AACETGM2 | |
| SCHEMBL2234378 | 0.87 | CTSK (0.47) | CTSKCTSLCTSBCTSS | |
| SCHEMBL6378831 | 0.87 | PPARA (0.41) | PNMTNPC1RAB9AACETGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153243-A1 | MODIFIED PEPTIDE AS TREM-1 INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-118359676-A | Modified peptides as Trem-1 inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-07-19 | — | — | CN | disclosed |