Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168371 | 0.87 | CTSK (0.40) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL26981184 | 0.87 | PNMT (0.41) | PNMTNPC1RAB9ACD274HTR7 | |
| SCHEMBL29168333 | 0.86 | PNMT (0.41) | PNMTNPC1RAB9ACD274HTR7 | |
| SCHEMBL6022733 | 0.85 | ITGB3 (0.44) | PNMTNPC1RAB9APTGER1PTGER4 | |
| SCHEMBL6022774 | 0.85 | ITGB3 (0.44) | PNMTNPC1RAB9APTGER1PTGER4 | |
| SCHEMBL27658685 | 0.82 | PNMT (0.38) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL28333729 | 0.82 | PNMT (0.38) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL28300337 | 0.82 | PNMT (0.38) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL31634803 | 0.81 | PNMT (0.45) | PNMTNPC1RAB9ACD274HTR7 | |
| SCHEMBL18764817 | 0.81 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153243-A1 | MODIFIED PEPTIDE AS TREM-1 INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-118359676-A | Modified peptides as Trem-1 inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-07-19 | — | — | CN | disclosed |