Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022733 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BPNMTABCB1PTGER1 | |
| SCHEMBL26981184 | 0.89 | PNMT (0.41) | ITGB3ITGA2BPNMTABCB1PTGER1 | |
| SCHEMBL28333729 | 0.89 | PNMT (0.38) | ITGB3ITGA2BPNMTABCB1PTGER1 | |
| SCHEMBL29168371 | 0.88 | CTSK (0.40) | ITGB3ITGA2BPNMTPTGER1PTGER4 | |
| SCHEMBL27658685 | 0.85 | PNMT (0.38) | ITGB3ITGA2BPNMTPTGER1PTGER4 | |
| SCHEMBL30940320 | 0.85 | PNMT (0.43) | PNMTABCB1PTGER1PTGER4PTGER3 | |
| SCHEMBL8775766 | 0.84 | PNMT (0.38) | ITGB3ITGA2BPNMTNPC1RAB9A | |
| SCHEMBL31710582 | 0.83 | NPC1 (0.39) | ITGB3ITGA2BPNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28300337 | 0.82 | PNMT (0.38) | ITGB3ITGA2BPNMTPTGER1PTGER4 | |
| Triphenylmethanol SCHEMBL15361971 | 0.82 | PNMT (0.36) | ITGB3ITGA2BPNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759786-B1 | SOMATOSTATIN BINDING PEPTIDE-METAL CHELATE CONJUGATES | DIATIDE INC (US) | 2006-09-27 | — | — | EP | disclosed |
| US-5985241-A | DIAGNOSTIC AND RADIODIAGNOSTIC AGENTS, FORMED BY REACTING TECHNETIUM-99M WITH A SOMATOSTATIN RECEPTOR-BINDING PEPTIDE | DIATIDE, INC. (US) | 1999-11-16 | — | — | US | disclosed |
| US-5981477-A | ADMINISTERING TO THE MAMMAL BEARING SOMATOSTATIN RECEPTOR EXPRESSING TUMOR, A METAL ION COMPLEXED SOMATOSTATIN RECEPTOR BINDING CYCLIC PEPTIDE | DIATIDE, INC. (US) | 1999-11-09 | — | — | US | disclosed |
| US-5972308-A | REACTING TECHNETIUM-99 WITH A CYCLIC OLIGOPEPTIDE HAVING AMINO ACID UNITS CONTAINING A MERCAPTAN GROUP ATTACHED TO THE RING THROUGH A HOMOCYSTEINE UNIT. | DIATIDE, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5965108-A | CYCLIC PEPTIDE-METAL COMPLEX SPECIFICALLY BINDS TO SURFACE SOMATOSTATIN RECEPTOR-EXPRESSING CELLS; RADIOLOGY; SCINTIGRAPHY; ANTITUMOR,-CARCINOGENIC AND METASTATIC AGENTS; STABILITY | DIATIDE, INC. (US) | 1999-10-12 | — | — | US | disclosed |
| US-5783170-A | Peptide-metal chelate conjugates | DIATIDE, INC. (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0759786-A1 | SOMATOSTATIN BINDING PEPTIDE-METAL CHELATE CONJUGATES | DIATECH, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031221-A1 | SOMATOSTATIN BINDING PEPTIDE-METAL CHELATE CONJUGATES | DIATECH, INC. (US) | 1995-11-23 | — | — | WO | disclosed |