SCHEMBL30940735

SCHEMBL30940735

CN(CCCN(CCc1ccc(F)cc1)C(=O)OC(C)(C)C)C[C@H]1C[C@H](O)[C@@H]2OC(C)(C)O[C@H]12

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 4/20 0.34
▸ PPARA Q07869 4/20 0.34
▸ PPARD Q03181 1/20 0.34
▸ CHRM1 P11229 3/20 0.32
▸ CHRM5 P08912 2/20 0.32
▸ CHRM3 P20309 2/20 0.32
▸ KDM1A O60341 3/20 0.31
▸ HDAC8 Q9BY41 1/20 0.31
▸ HDAC6 Q9UBN7 1/20 0.31
▸ CCR3 P51677 1/20 0.31
▸ CPB2 Q96IY4 1/20 0.31
▸ CHRM2 P08172 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30941778 0.86 CA14 (0.35) PPARGPPARAPPARDCHRM1CHRM5
SCHEMBL25049170 0.85 L3MBTL1 (0.36) —
SCHEMBL31617951 0.79 CPB2 (0.30) CPB2
SCHEMBL30941159 0.76 — —
SCHEMBL30940966 0.75 L3MBTL1 (0.33) —
SCHEMBL25046716 0.75 NNMT (0.37) —
SCHEMBL31617863 0.73 CPB2 (0.31) CPB2
SCHEMBL31617992 0.73 METTL3 (0.38) —
SCHEMBL25047599 0.72 CA14 (0.45) PPARGPPARAPPARDCHRM1CHRM5
SCHEMBL25047643 0.71 CA12 (0.43) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2025-06-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION KMT5A, KMT5B, KMT5C PPARG 4729/4885PPARA 4767/4885PPARD 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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