Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | PTGIR | P43119 | 7/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194978 | 0.83 | — | — | |
| SCHEMBL21384275 | 0.82 | ATF4 (0.38) | ITGB3ITGA2BPTGIRPDK2 | |
| SCHEMBL29755709 | 0.77 | ITGB3 (0.40) | HCRTR2ITGB3ITGA2BPTGIRADCY5 | |
| SCHEMBL8716708 | 0.75 | ITGB3 (0.39) | ITGB3ITGA2BPTGIRADCY5 | |
| SCHEMBL360541 | 0.74 | ITGB3 (0.41) | ITGB3ITGA2BPTGIR | |
| SCHEMBL1733927 | 0.74 | — | — | |
| SCHEMBL20721947 | 0.74 | ADCY5 (0.35) | ITGB3ITGA2BPDK2ADCY5 | |
| SCHEMBL20722083 | 0.74 | ADCY5 (0.35) | ITGB3ITGA2BPDK2ADCY5 | |
| SCHEMBL8560336 | 0.74 | ITGB3 (0.38) | ITGB3ITGA2BPTGIRADCY5 | |
| SCHEMBL1714642 | 0.74 | APP (0.34) | HCRTR2ENPP2APPCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134541-A1 | HETEROCYCLIC COMPOUNDS AS ENT INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2024-06-27 | — | — | WO | disclosed |