SCHEMBL360541

SCHEMBL360541

O=C(O)COC1CCCC1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 4/20 0.41
ITGA2B P08514 4/20 0.41
THRB P10828 3/20 0.40
THRA P10827 2/20 0.40
PTGIR P43119 1/20 0.37
PTGDR2 Q9Y5Y4 3/20 0.37
EPHX1 P07099 2/20 0.36
TSHR P16473 1/20 0.36
CTH P32929 1/20 0.36
CBS P35520 1/20 0.36
THPO P40225 1/20 0.36
ATF4 P18848 1/20 0.36
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
CYP2C19 P33261 1/20 0.34
NAAA Q02083 1/20 0.34
PTGDR Q13258 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1734827 0.98 THRA (0.42) ITGB3ITGA2BTHRBTHRAPTGIR
SCHEMBL15159536 0.98 THRA (0.42) ITGB3ITGA2BTHRBTHRAPTGIR
SCHEMBL9132526 0.98 THRA (0.42) ITGB3ITGA2BTHRBTHRAPTGIR
SCHEMBL16204628 0.98 THRA (0.42) ITGB3ITGA2BTHRBTHRAPTGIR
SCHEMBL27451178 0.98 THRA (0.42) ITGB3ITGA2BTHRBTHRAPTGIR
SCHEMBL24564741 0.98 THRA (0.42) ITGB3ITGA2BTHRBTHRAPTGIR
SCHEMBL1733927 0.95
SCHEMBL9194978 0.90
SCHEMBL11918037 0.83 ITGB3 (0.38) ITGB3ITGA2BTHRBTHRAPTGIR
SCHEMBL432285 0.83 ITGB3 (0.38) ITGB3ITGA2BTHRBTHRAPTGIR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388604-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2025-12-25 US disclosed
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 US disclosed
EP-4572762-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP disclosed
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 EP disclosed
CN-114671864-B Heteroaryl substituted pyridines and methods of use 艾伯维公司 2025-04-08 CN disclosed
EP-3541802-B1 ALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR AMGEN INC (US) 2025-01-01 EP disclosed
US-20240400562-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LHOTSE BIO, INC. 2024-12-05 US disclosed
EP-4419509-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY Lhotse Bio, Inc. (US) 2024-08-28 EP disclosed
CN-118339149-A Compounds and compositions for treating conditions associated with LPA receptor activity 罗特斯生物公司 2024-07-12 CN disclosed
US-20240132513-A1 BENZAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT AGENEBIO, INC. 2024-04-25 US disclosed
EP-1288280-B1 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH & CIE (CH) 2007-01-03 EP disclosed
CN-1184214-C Alpha-acyl and alpha-heteroatom substituted phenylacetamide glucokinase activators HOFFMANN LA ROCHE (CH) 2005-01-12 CN disclosed
US-6720295-B2 COMPOUND CONTAINING CYCLOPENT(EN)YL RING FIRMENICH SA (CH) 2004-04-13 US disclosed
CN-1443177-A Alpha-acyl and alpha-heteroatom-substituted benzene acetamide glucokinase activators HOFFMANN LA ROCHE (CH) 2003-09-17 CN disclosed
US-20030087775-A1 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH SA (CH) 2003-05-08 US disclosed
EP-1288280-A2 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH SA (CH) 2003-03-05 EP disclosed
US-4735932-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1988-04-05 US disclosed
US-4735932-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1988-04-05 US disclosed
US-4735932-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1988-04-05 US disclosed
CN-85107017-A Preparation three ring pyridazinones dihydro compounds and the method that contains the pharmaceutical composition of this compound 1987-04-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400562-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LPAR1, LPAR2, LPAR6 ITGB3 2847/4885ITGA2B 2410/4885THRB 1199/4885
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 ITGB3 672/4885ITGA2B 243/4885THRB 3265/4885
US-20250388604-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B ITGB3 2718/4885ITGA2B 3184/4885THRB 861/4885
US-20240132513-A1 BENZAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT GABRA5, GRM5, GABRB1 ITGB3 922/4885ITGA2B 771/4885THRB 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.