Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30323931 | 1.00 | LMNA (0.48) | LMNAMAPTKMT2AMEN1JAK2 | |
| SCHEMBL28622408 | 0.94 | MAPT (0.49) | LMNAMAPTKMT2AMEN1JAK2 | |
| SCHEMBL30323980 | 0.80 | MAPT (0.47) | LMNAMAPTKMT2AMEN1JAK2 | |
| SCHEMBL24042553 | 0.78 | NAMPT (0.58) | LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL29232536 | 0.77 | ALDH1A1 (0.57) | MAPTKDM4EALDH1A1 | |
| SCHEMBL23320569 | 0.76 | LMNA (0.54) | LMNACYP19A1 | |
| SCHEMBL281590 | 0.76 | RAB9A (0.59) | LMNAMAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL30943258 | 0.74 | LMNA (0.56) | LMNAMAPTALDH1A1CYP19A1NPC1 | |
| SCHEMBL23320409 | 0.74 | LMNA (0.56) | LMNAMAPTKMT2AMEN1KDM4E | |
| SCHEMBL28922327 | 0.74 | LMNA (0.56) | LMNAMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |