Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530525 | 1.00 | KMT2A (0.67) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL26458871 | 0.80 | NPC1 (1.00) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL28527311 | 0.78 | NPC1 (0.43) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL28520792 | 0.78 | P2RX7 (0.42) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL30944412 | 0.78 | NPC1 (0.43) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL30944327 | 0.78 | P2RX7 (0.42) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL30597547 | 0.76 | NPC1 (0.85) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL15274399 | 0.74 | KMT2A (0.66) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL30944385 | 0.72 | RAB9A (0.61) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL30944332 | 0.72 | CASP3 (0.67) | KMT2ANPC1RAB9AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |