SCHEMBL30945145

SCHEMBL30945145

Cc1ccc(C(=O)Nc2ncc(Br)s2)c(O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 2/20 0.67
FBP1 P09467 5/20 0.51
KDR P35968 1/20 0.47
LMNA P02545 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
PKM P14618 1/20 0.47
PLG P00747 3/20 0.46
KLK1 P06870 2/20 0.46
KLK6 Q92876 2/20 0.46
F2 P00734 1/20 0.45
F10 P00742 1/20 0.45
PLAU P00749 1/20 0.45
PLAT P00750 1/20 0.45
MAPK10 P53779 1/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14380922 0.90 STAT3 (0.67) STAT3FBP1LMNANPC1RAB9A
SCHEMBL13524033 0.84 STAT3 (0.48) STAT3FBP1LMNANPC1RAB9A
SCHEMBL13524050 0.84 FBP1 (0.50) STAT3FBP1LMNANPC1RAB9A
SCHEMBL23026965 0.84 STAT3 (0.67) STAT3KDRLMNANPC1RAB9A
SCHEMBL13524042 0.84 NPC1 (0.50) STAT3FBP1LMNANPC1RAB9A
SCHEMBL13524036 0.82 LMNA (0.50) STAT3FBP1LMNANPC1RAB9A
SCHEMBL4755924 0.81 STAT3 (0.63) STAT3FBP1KDRLMNANPC1
SCHEMBL13524040 0.81 STAT3 (0.64) STAT3FBP1LMNANPC1RAB9A
SCHEMBL29908284 0.80 STAT3 (1.00) STAT3LMNANPC1RAB9ASMN1; SMN2
SCHEMBL5795075 0.80 STAT3 (1.00) STAT3LMNANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630553-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CARDIOVASCULAR DISEASE ProQR Therapeutics II B.V. (NL) 2025-10-15 EP disclosed
WO-2024121373-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CARDIOVASCULAR DISEASE PROQR THERAPEUTICS II B.V. (NL) 2024-06-13 WO disclosed