Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 11/20 | 0.68 |
| ▸ | RAB9A | P51151 | 11/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | PKM | P14618 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MLNR | O43193 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908284 | 1.00 | STAT3 (1.00) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5797958 | 0.91 | STAT3 (1.00) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29908285 | 0.91 | STAT3 (1.00) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25063001 | 0.89 | STAT3 (0.80) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28574896 | 0.88 | STAT3 (0.78) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25063050 | 0.87 | STAT3 (0.80) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5795728 | 0.83 | NPC1 (0.75) | STAT3NPC1RAB9AMEN1KMT2A | |
| Tizoxanide SCHEMBL375440 | 0.83 | STAT3 (1.00) | STAT3NPC1RAB9AMEN1KMT2A | |
| Tizoxanide SCHEMBL29367981 | 0.83 | STAT3 (1.00) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22680776 | 0.81 | NPC1 (1.00) | STAT3NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11850237-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2023-12-26 | — | — | US | disclosed |
| US-11850237-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2023-12-26 | — | — | US | disclosed |
| CN-116456980-A | Application of thiazole compounds in preparation of medicines for treating and preventing cancers | 北京大学 | 2023-07-18 | — | — | CN | disclosed |
| EP-3895706-A1 | THIAZOLINIDE COMPOUNDS FOR TREATING NON-INFLUENZA VIRAL INFECTIONS | Romark Laboratories, L.C. (US) | 2021-10-20 | — | — | EP | disclosed |
| US-20210177809-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2021-06-17 | — | — | US | disclosed |
| CN-112957358-A | Application of nitazoxanide and derivatives thereof in preparing medicines for preventing and treating bone destructive diseases | 北京大学第三医院（北京大学第三临床医学院） | 2021-06-15 | — | — | CN | disclosed |
| US-10912768-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2021-02-09 | — | — | US | disclosed |
| US-20190307730-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2019-10-10 | — | — | US | disclosed |
| US-10363243-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2019-07-30 | — | — | US | disclosed |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2018-03-22 | — | — | US | disclosed |
| US-20160228415-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2016-08-11 | — | — | US | disclosed |
| US-9345690-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150250768-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2015-09-10 | — | — | US | disclosed |
| US-9023877-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2015-05-05 | — | — | US | disclosed |
| US-9023877-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. | 2010-12-30 | — | — | US | disclosed |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. | 2010-12-30 | — | — | US | disclosed |
| WO-2010151577-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2010-12-29 | — | — | WO | disclosed |
| US-20060194853-A1 | Alkyl benzamides | LAMINAR DIRECT CAPITAL, L.L.C. | 2006-08-31 | — | — | US | disclosed |
| WO-2006042195-A1 | ALKYL BENZAMIDES | ROMARK LABORATORIES, L.C. (US) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250768-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-10912768-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20210177809-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20190307730-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-11850237-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20160228415-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20060194853-A1 | Alkyl benzamides | SAMHD1, PIGS, BTD | STAT3 2811/4885NPC1 669/4885RAB9A 1728/4885 |
| US-10363243-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.