Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326519 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNA4DDB1CRBN | |
| SCHEMBL29909305 | 0.81 | TRPV6 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL1655533 | 0.81 | TRPV6 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL30630185 | 0.76 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL20757503 | 0.76 | CHRNB2 (0.42) | CHRNB2CHRNA4DDB1CRBN | |
| SCHEMBL25702645 | 0.76 | KDM4E (0.54) | — | |
| SCHEMBL23517959 | 0.76 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL254836 | 0.76 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL13949329 | 0.76 | CHRNB2 (0.51) | CHRNB2CHRNA4 | |
| SCHEMBL31076325 | 0.76 | CHRNB2 (0.46) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199587-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199587-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP1A1, CYP4B1 | CHRNB2 2449/4885CHRNA4 2283/4885DDB1 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.