Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23517959 | 1.00 | CHRNB2 (0.33) | CHRNB2CHRNA4KDM4EGLAHTT | |
| SCHEMBL31546836 | 0.85 | PRMT5 (0.37) | CHRNB2CHRNA4KDM4EGLAHTT | |
| SCHEMBL29909305 | 0.81 | TRPV6 (0.42) | CHRNB2CHRNA4KDM4EGLAHTT | |
| SCHEMBL1655533 | 0.81 | TRPV6 (0.42) | CHRNB2CHRNA4KDM4EGLAHTT | |
| SCHEMBL31469673 | 0.81 | KDM4E (0.37) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL12609562 | 0.76 | CHRNB2 (0.45) | CHRNB2CHRNA4KMT2ATDP1 | |
| SCHEMBL30630170 | 0.76 | DRD2 (0.47) | KDM4ESMN1; SMN2DRD2DRD3 | |
| SCHEMBL29364367 | 0.76 | CHRNB2 (0.45) | CHRNB2CHRNA4KMT2ATDP1 | |
| SCHEMBL24746466 | 0.76 | DRD2 (0.47) | KDM4ESMN1; SMN2DRD2DRD3 | |
| SCHEMBL25326519 | 0.76 | CHRNB2 (0.41) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007863-A1 | 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-01-09 | — | — | WO | disclosed |
| CN-119241532-A | 1H-pyrazolo [4,3-c ] pyridine compound, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-117120090-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-11-24 | — | — | CN | disclosed |