SCHEMBL30946509

SCHEMBL30946509

Cc1cc(F)c2c(c1Br)CC(=O)N2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
HBB P68871 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
DRD2 P14416 1/20 0.32
DRD1 P21728 1/20 0.32
DRD4 P21917 1/20 0.32
DRD5 P21918 1/20 0.32
DRD3 P35462 1/20 0.32
GSK3B P49841 2/20 0.31
CMA1 P23946 1/20 0.31
AHR P35869 1/20 0.31
GRIA1 P42261 1/20 0.30
CACNG8 Q8WXS5 1/20 0.30
CCNB2 O95067 1/20 0.30
CDK1 P06493 1/20 0.30
CCNB1 P14635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22691576 0.80 DRD2 (0.32) MEN1MAPTALOX15ALOX12HBB
SCHEMBL30946450 0.80
SCHEMBL30946373 0.78 GRIA1 (0.33) DRD2DRD1DRD4DRD5DRD3
SCHEMBL22691798 0.74 DRD2 (0.37) MEN1MAPTKMT2ADRD2DRD1
SCHEMBL23641402 0.71 GSK3B (0.42) MEN1MAPTALOX15ALOX12HBB
SCHEMBL29422962 0.70 DRD2 (0.37) MEN1KMT2ADRD2DRD1DRD4
SCHEMBL19210878 0.70 DRD2 (0.37) MEN1KMT2ADRD2DRD1DRD4
SCHEMBL5504779 0.69 PGR (0.36) MAPTGRIA1
SCHEMBL26640480 0.69 DRD2 (0.41) MEN1KMT2ADRD2DRD1DRD4
SCHEMBL31528295 0.68 TGM2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634161-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics Inc. (US) 2025-10-22 EP disclosed
WO-2024130166-A2 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2024-06-20 WO disclosed