Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499002 | 0.77 | TDP2 (0.38) | PGRPOLBCCR6CYP1A2GRIN2D | |
| SCHEMBL22691576 | 0.75 | DRD2 (0.32) | ALDH1A1MAPT | |
| SCHEMBL5358791 | 0.71 | POLB (0.48) | PGRPOLBCYP3A4TSHRTDP1 | |
| SCHEMBL30946509 | 0.69 | MEN1 (0.34) | MAPTGRIA1 | |
| SCHEMBL5789641 | 0.68 | GPR35 (0.44) | PGRPOLBCYP1A2GRIN2DGRIN3B | |
| SCHEMBL3139883 | 0.68 | TDP2 (0.41) | PGRCYP1A2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL19737628 | 0.68 | GPR35 (0.44) | PGRPOLBCYP1A2GRIN2DGRIN3B | |
| SCHEMBL1163368 | 0.68 | TDP2 (0.51) | PGRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL30893029 | 0.68 | CYP11B1 (0.46) | PGRCCR6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL27146946 | 0.68 | CYP11B1 (0.46) | PGRCCR6CYP1A2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869030-A1 | 7-FLUORO-1,3-DIHYDRO-INDOL-2-ONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006106427-A1 | 7-FLUORO-1,3-DIHYDRO-INDOL-2-ONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-12 | — | — | WO | disclosed |