Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL6227317 | 0.92 | TSHR (0.56) | LMNATSHRTP53EGLN1EGLN3 | |
| Methacrylic Acid SCHEMBL5013791 | 0.92 | LMNA (0.62) | LMNATSHRTP53EGLN1EGLN3 | |
| Methacrylic Acid SCHEMBL9726633 | 0.92 | LMNA (0.62) | LMNATSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL382027 | 0.92 | TSHR (0.56) | LMNATSHRTP53EGLN1EGLN3 | |
| Methacrylic Acid SCHEMBL5964487 | 0.92 | LMNA (0.62) | LMNATSHRTP53EGLN1EGLN3 | |
| Methacrylic Acid SCHEMBL23071293 | 0.92 | LMNA (0.62) | LMNATSHRTP53EGLN1EGLN3 | |
| Methacrylic Acid SCHEMBL9681348 | 0.92 | LMNA (0.62) | LMNATSHRTP53EGLN1EGLN3 | |
| Methacrylic Acid SCHEMBL137716 | 0.92 | LMNA (0.62) | LMNATSHRTP53EGLN1EGLN3 | |
| Methacrylic Acid SCHEMBL9066064 | 0.92 | LMNA (0.62) | LMNATSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL63722 | 0.92 | TSHR (0.56) | LMNATSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4616027-A1 | IMPROVED SCALE INHIBITION FOR PULP DIGESTERS | Ecolab USA Inc. (US) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024155511-A1 | IMPROVED SCALE INHIBITION FOR PULP DIGESTERS | ECOLAB USA INC. (US) | 2024-07-25 | — | — | WO | disclosed |
| US-20240247439-A1 | SCALE INHIBITION FOR PULP DIGESTERS | ECOLAB USA INC. (US) | 2024-07-25 | — | — | US | disclosed |