Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 7/20 | 0.36 |
| ▸ | SCD | O00767 | 4/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948194 | 0.84 | CA12 (0.47) | IL4I1P2RX7MAPTARHTT | |
| SCHEMBL30948260 | 0.82 | IL4I1 (0.46) | IL4I1DDB1CRBNP2RX7GRM4 | |
| SCHEMBL30948035 | 0.81 | IL4I1 (0.40) | IL4I1SCD5SCDNPC1RAB9A | |
| SCHEMBL30948108 | 0.78 | IL4I1 (0.41) | IL4I1DDB1CRBNP2RX7GRM4 | |
| SCHEMBL30948054 | 0.76 | IL4I1 (0.52) | IL4I1SCD5SCDCXCR1ALDH1A1 | |
| SCHEMBL27163527 | 0.76 | IL4I1 (0.55) | IL4I1SCD5SCDCXCR1 | |
| SCHEMBL30948291 | 0.72 | IL4I1 (0.65) | IL4I1SCD5SCDALDH1A1NPC1 | |
| SCHEMBL30948248 | 0.71 | IL4I1 (0.48) | IL4I1MAPTHTTCA12CA9 | |
| SCHEMBL30948347 | 0.70 | IL4I1 (0.39) | IL4I1DDB1CRBN | |
| SCHEMBL30948008 | 0.70 | IL4I1 (0.46) | IL4I1SCD5ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | IL4I1 1/4885SCD5 4879/4885SCD 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.