Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948262 | 0.86 | USP1 (0.40) | GRM2CHRM1ADORA1TLR7HCRTR1 | |
| SCHEMBL30947960 | 0.85 | IL4I1 (0.47) | GRM2CHRM1ADORA1TLR7IL4I1 | |
| SCHEMBL30947905 | 0.84 | CHRM1 (0.49) | GRM2CHRM1IL4I1HCRTR1HCRTR2 | |
| SCHEMBL30948347 | 0.78 | IL4I1 (0.39) | IL4I1PRMT5DYRK1A | |
| SCHEMBL30948086 | 0.75 | IL4I1 (0.34) | CHRM1ADORA1TLR7IL4I1 | |
| SCHEMBL30948316 | 0.73 | TP53 (0.47) | IL4I1 | |
| SCHEMBL30948108 | 0.71 | IL4I1 (0.41) | IL4I1HCRTR2SMN1; SMN2 | |
| SCHEMBL30947967 | 0.70 | CHRM1 (0.50) | GRM2CHRM1IL4I1PRMT5HCRTR1 | |
| SCHEMBL30948128 | 0.68 | IL4I1 (0.50) | GRM2CHRM1IL4I1KCNH2HCRTR1 | |
| SCHEMBL30948147 | 0.68 | IL4I1 (0.50) | IL4I1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | GRM2 4617/4885CHRM1 3382/4885ADORA1 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.