Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | MARS1 | P56192 | 2/20 | 0.47 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25077985 | 1.00 | LMNA (0.49) | LMNAL3MBTL1NAPRTP4HTMMARS1 | |
| SCHEMBL30949240 | 0.86 | MARS1 (0.48) | L3MBTL1MARS1ALDH1A1EP300KAT2B | |
| SCHEMBL31747771 | 0.82 | POLB (0.47) | ALDH1A1CNR1CNR2PLK4ROCK2 | |
| SCHEMBL25078379 | 0.82 | POLB (0.47) | ALDH1A1CNR1CNR2PLK4ROCK2 | |
| SCHEMBL924712 | 0.78 | RPA1 (0.56) | LMNAL3MBTL1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL17011147 | 0.78 | MARS1 (0.53) | LMNAL3MBTL1NAPRTP4HTMMARS1 | |
| SCHEMBL25078489 | 0.75 | NAPRT (0.45) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| SCHEMBL31459727 | 0.75 | MARS1 (0.50) | LMNAL3MBTL1NAPRTP4HTMMARS1 | |
| SCHEMBL3193063 | 0.74 | ALKBH2 (0.53) | LMNAL3MBTL1NAPRTP4HTMMARS1 | |
| SCHEMBL31524136 | 0.74 | ALKBH2 (0.53) | LMNAL3MBTL1NAPRTP4HTMMARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119600-A | SOS1 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-05-31 | — | — | CN | disclosed |