SCHEMBL31524136

SCHEMBL31524136

O=C(O)c1ccn(-c2ccccn2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH2 Q6NS38 1/20 0.53
EGLN1 Q9GZT9 1/20 0.53
LMNA P02545 2/20 0.52
NAPRT Q6XQN6 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
KDM5A P29375 2/20 0.44
KDM4C Q9H3R0 2/20 0.44
KDM5B Q9UGL1 2/20 0.44
KDM2B Q8NHM5 1/20 0.44
MARS1 P56192 1/20 0.43
KDM4A O75164 1/20 0.43
MTOR P42345 2/20 0.42
GRM5 P41594 1/20 0.42
APOBEC3A P31941 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
RPTOR Q8N122 1/20 0.40
MLST8 Q9BVC4 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193063 1.00 ALKBH2 (0.53) ALKBH2EGLN1LMNANAPRTP4HTM
SCHEMBL2572281 0.85 MARS1 (0.44) ALKBH2EGLN1LMNANAPRTP4HTM
SCHEMBL12571538 0.81 LMNA (0.47) EGLN1LMNANAPRTP4HTML3MBTL1
SCHEMBL12571515 0.79 ELOVL1 (0.46) EGLN1LMNANAPRTP4HTML3MBTL1
SCHEMBL12571521 0.79 SLC6A7 (0.38) ALKBH2EGLN1LMNANAPRTP4HTM
SCHEMBL12571530 0.79 KDM4E (0.50) ALKBH2EGLN1LMNANAPRTP4HTM
SCHEMBL12571506 0.78 ALDH1A1 (0.52) LMNAKMT2AKDM4ETSHRSMN1; SMN2
SCHEMBL1063920 0.77 CYP2C9 (0.61) ALKBH2LMNAL3MBTL1KMT2AKDM4E
SCHEMBL16517279 0.76 KDM5A (0.44) EGLN1LMNANAPRTP4HTML3MBTL1
SCHEMBL31587124 0.76 KDM5A (0.50) ALKBH2EGLN1KDM5AKDM4CKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113382984-B Preparation method of N-phenylpyrazole-1-carboxamide FMC公司 2025-03-14 CN disclosed