Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | DHPS | P49366 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949556 | 0.81 | P2RX7 (0.33) | P2RX7AHRPARP1 | |
| SCHEMBL30949501 | 0.74 | HCRTR1 (0.36) | PARP1 | |
| SCHEMBL25025782 | 0.72 | NR4A2 (0.49) | CETP | |
| SCHEMBL30949559 | 0.67 | CETP (0.42) | P2RX7CETP | |
| SCHEMBL30949560 | 0.67 | CETP (0.42) | P2RX7CETP | |
| SCHEMBL25026083 | 0.65 | NR4A2 (0.53) | — | |
| SCHEMBL13987128 | 0.65 | NR4A2 (0.47) | P2RX7AHR | |
| SCHEMBL30949600 | 0.63 | AHR (0.46) | AHRPARP1 | |
| SCHEMBL30949580 | 0.63 | GAA (0.51) | — | |
| SCHEMBL30949589 | 0.63 | GAA (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |