Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987128 | 0.80 | NR4A2 (0.47) | AHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6422575 | 0.79 | F7 (0.43) | AHRPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL29783527 | 0.78 | NOTUM (0.41) | AHRPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL21819005 | 0.78 | PARP1 (0.40) | AHRPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL27222251 | 0.78 | NOTUM (0.41) | AHRPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL30949552 | 0.76 | DHPS (0.39) | AHRPARP1HDAC1HDAC6MTNR1A | |
| SCHEMBL30474626 | 0.72 | CA12 (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10415958 | 0.72 | CA12 (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30949503 | 0.72 | CNR2 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL6923181 | 0.71 | NOS1 (0.49) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |