SCHEMBL3094971

SCHEMBL3094971

CCc1ccc(C2=NC(c3ccccc3Cl)(n3c(-c4ccccc4Cl)nc(-c4ccc(CC)cc4)c3-c3ccc(CC)cc3)N=C2c2ccc(CC)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.36
SMN1; SMN2 Q16637 1/20 0.32
GPBAR1 Q8TDU6 1/20 0.32
CRHR1 P34998 1/20 0.32
AKT1 P31749 2/20 0.32
AKT2 P31751 2/20 0.32
DCTPP1 Q9H773 1/20 0.31
TP53 P04637 1/20 0.31
TDP2 O95551 2/20 0.31
CDC7 O00311 1/20 0.31
DBF4 Q9UBU7 1/20 0.31
S1PR3 Q99500 1/20 0.31
HSP90AA1 P07900 1/20 0.30
NPSR1 Q6W5P4 2/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30358503 0.90 HSD11B1 (0.47) HSD11B1CRHR1
SCHEMBL3089637 0.90 HSD11B1 (0.47) HSD11B1CRHR1
SCHEMBL30358509 0.89 L3MBTL1 (0.39) HSD11B1SMN1; SMN2POLB
SCHEMBL3094986 0.89 L3MBTL1 (0.39) HSD11B1SMN1; SMN2POLB
SCHEMBL3089568 0.89 HSD11B1 (0.50) HSD11B1
SCHEMBL30358502 0.89 HSD11B1 (0.50) HSD11B1
SCHEMBL29359500 0.88 HSD11B1 (0.37) HSD11B1SMN1; SMN2AKT1AKT2
SCHEMBL29749791 0.88 HSD11B1 (0.37) HSD11B1SMN1; SMN2AKT1AKT2
SCHEMBL307038 0.88 HSD11B1 (0.37) HSD11B1SMN1; SMN2AKT1AKT2
SCHEMBL30358506 0.86 GAA (0.33) HSD11B1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317942-A1 THIOL-CONTAINING COMPOSITION, PHOTOSETTING COMPOSITION, AND THERMOSETTING COMPOSITION RESONAC CORPORATION (JP) 2024-09-26 US disclosed
EP-4375302-A1 THIOL-CONTAINING COMPOSITION, PHOTOCURABLE COMPOSITION, AND THERMOSETTING COMPOSITION Resonac Corporation (JP) 2024-05-29 EP disclosed
WO-2023003011-A1 THIOL-CONTAINING COMPOSITION, PHOTOCURABLE COMPOSITION, AND THERMOSETTING COMPOSITION 昭和電工株式会社 2023-01-26 WO disclosed
EP-1478668-B1 THIOL COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPOSITION AND PHOTOSENSITIVE COMPOSITION SHOWA DENKO KK (JP) 2013-04-10 EP disclosed
US-8283095-B2 Thiourethane compound and photosensitive resin composition SHOWA DENKO K.K. (JP) 2012-10-09 US disclosed
US-20100233596-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION SHOWA DENKO K.K. (JP) 2010-09-16 US disclosed
EP-2055726-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Showa Denko K.K. (JP) 2009-05-06 EP disclosed
US-7341828-B2 Thiol compound, photopolymerization initiator composition and photosensitive composition SHOWA DENKO K.K. (JP) 2008-03-11 US disclosed
US-20050153231-A1 Thiol compound, photopolymerization initiator composition and photosensitive composition SHOWA DENKO K.K. (JP) 2005-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233596-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION RCOR3, CBR3, TAS2R3 HSD11B1 3197/4885SMN1; SMN2 3675/4885GPBAR1 3383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.