Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.32 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | AGER | Q15109 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27246069 | 1.00 | MAPK14 (0.34) | MAPK14TNIKNPC1CTSLELANE | |
| SCHEMBL31720195 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL25150044 | 0.72 | DYRK1A (0.54) | TGFBR1AGERHDAC6 | |
| SCHEMBL22125578 | 0.71 | GGPS1 (0.42) | MAPK14FDPSGGPS1AGER | |
| SCHEMBL6176928 | 0.66 | ADORA2A (0.44) | MAPK14FGFR1FGFR4AGER | |
| SCHEMBL30899626 | 0.64 | GGPS1 (0.43) | MAPK14FDPSGGPS1TGFBR1 | |
| SCHEMBL25332641 | 0.63 | HCAR1 (0.31) | — | |
| SCHEMBL31748263 | 0.63 | TDP1 (0.63) | FDPSGGPS1AGER | |
| SCHEMBL22125589 | 0.62 | GGPS1 (0.41) | MAPK14NPC1CASP1RAB9AFDPS | |
| SCHEMBL28318535 | 0.62 | CDK9 (0.35) | TNIKTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611890-A1 | 4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF | BioSplice Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097391-A1 | 4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF | BIOSPLICE THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |