SCHEMBL30951245

SCHEMBL30951245

CC(=O)c1nc(C)c(N)cc1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.39
CFTR P13569 1/20 0.36
IKBKB O14920 2/20 0.36
KMT2A Q03164 5/20 0.34
KDM4E B2RXH2 4/20 0.34
MEN1 O00255 3/20 0.34
ALDH1A1 P00352 3/20 0.34
USP2 O75604 1/20 0.34
MAPT P10636 1/20 0.34
TP53 P04637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GAA P10253 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
PTGS2 P35354 1/20 0.32
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26850758 0.74 CFTR (0.39) CFTRIKBKBKMT2AKDM4EMEN1
SCHEMBL27194684 0.73 TERT (0.33) SMN1; SMN2KDM4EALDH1A1MAPTGAA
SCHEMBL11978271 0.73 CFTR (0.44) SMN1; SMN2CFTRIKBKB
SCHEMBL30259615 0.73 CFTR (0.44) SMN1; SMN2CFTRIKBKB
SCHEMBL30951222 0.71 MAPK14 (0.42) SMN1; SMN2KMT2AKDM4EMEN1MAPT
SCHEMBL20303036 0.70 SMN1; SMN2 (0.38) SMN1; SMN2KMT2AALDH1A1PTGS2
SCHEMBL18109486 0.70 NPSR1 (0.44) SMN1; SMN2CFTRKDM4EALDH1A1MAPT
SCHEMBL30608970 0.70 NPSR1 (0.44) SMN1; SMN2CFTRKDM4EALDH1A1MAPT
SCHEMBL17594237 0.69 GABRP (0.40) SMN1; SMN2KMT2AKDM4EMEN1ALDH1A1
SCHEMBL18289573 0.69 CFTR (0.47) SMN1; SMN2CFTRIKBKBKMT2AMAP4K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634188-A1 PYRIMIDINONE DERIVATIVES AS PESTICIDAL COMPOUNDS BASF SE (DE) 2025-10-22 EP disclosed
WO-2024126117-A1 PYRIMIDINONE DERIVATIVES AS PESTICIDAL COMPOUNDS BASF SE (DE) 2024-06-20 WO disclosed