Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GPR3 | P46089 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727666 | 1.00 | KDM4E (0.52) | KDM4EGPR3ADORA3TOP2APDPK1 | |
| SCHEMBL16114858 | 0.79 | EGFR (0.37) | KDM4EGPR3ADORA3 | |
| SCHEMBL5741090 | 0.78 | KDM4E (0.52) | KDM4EGPR3ADORA3TOP2APDPK1 | |
| SCHEMBL30549447 | 0.77 | PARP1 (0.42) | KDM4EGPR3PDPK1CYP1A2 | |
| SCHEMBL4900470 | 0.76 | KDM4E (0.47) | KDM4EGPR3PDGFRBPDGFRA | |
| SCHEMBL10667809 | 0.76 | LMNA (0.59) | KDM4ECYP1A2 | |
| SCHEMBL4932780 | 0.75 | LMNA (0.40) | KDM4E | |
| Iodide SCHEMBL10698948 | 0.75 | LMNA (0.58) | KDM4ECYP1A2 | |
| Bromide SCHEMBL10699147 | 0.75 | LMNA (0.58) | KDM4ECYP1A2 | |
| SCHEMBL253096 | 0.73 | GPR3 (0.50) | KDM4EGPR3TOP2APDPK1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076605-A | Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof | 洛蒙治疗公司 | 2024-05-24 | — | — | CN | disclosed |