Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 8/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.46 |
| ▸ | ITGAL | P20701 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490600 | 0.88 | PLA2G4A (0.76) | PLA2G4AMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3681764 | 0.82 | PLA2G4A (0.78) | PLA2G4AMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3681767 | 0.82 | PLA2G4A (0.78) | PLA2G4AMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2918644 | 0.81 | TSHR (0.55) | PLA2G4AMAPTHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL30779749 | 0.81 | TSHR (0.55) | PLA2G4AMAPTHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL2918642 | 0.81 | TSHR (0.55) | PLA2G4AMAPTHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL16960373 | 0.80 | MEN1 (0.51) | PLA2G4AMAPTHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL2785447 | 0.79 | ALDH5A1 (0.63) | PLA2G4AMAPTHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL2785445 | 0.79 | ALDH5A1 (0.63) | PLA2G4AMAPTHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL10780080 | 0.79 | MAPT (0.64) | PLA2G4AMAPTHDAC6ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630114-A1 | NEW CYANOPYRIDINE KHK INHIBITOR COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121183-A1 | NEW CYANOPYRIDINE KHK INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-06-13 | — | — | WO | disclosed |